Material Signal Loss Range Reduction
Interior Wall (Sheetrock) 4.5dB 10‐12%
Standard Slab Door (Hollow core) 5.5dB 10‐15%
Standard Slab Door (Solid core) 8dB 15‐20%
Brick (Decorative 3.5") 12dB 45%
Open Field @ 30ft 4dB 5%
Interior Window (Glass) 1dB 3%
Masonry Structural Block (6") 14dB 45‐55%

This is a general rule of thumb of signal loss you can expect through certain materials

Might also be worth checking that 1 Q50 is showing as a Primary & 1 as a secondary controller & that you optimise the primary before you optimise the secondary.
also if you have made any changes in the config you must re-upload the config to both remotes as each time you change something the config is given a unique ID number