Thanks for any suggestions, Brad.

Room 1 =

• 4x4 HDMI matrix (goes to AVR, PJ and two HDMI splitters)
• Primary HDMI video source (HTPC)
• Secondary HDMI video source (Nvidia Shield)
• Denon AVR
• Projector
• Wall-control for whole-house amp with IR control

Room 2 =

• TV with IR
• Two computer monitors, which I haven't quite figured out how to turn on/off since they have no IR. But they do power on/off with AC on/off.
• Six channel whole-house amp with IR remote & RS232 and each channel can be turned on/off remotely.
• Wall-control for whole-house amp with IR control

Room 4 =

• TV with IR
• Two computer monitors, which I haven't quite figured out how to turn on/off since they have no IR. But they do power on/off with AC on/off.
• Wall-control for whole-house amp with IR control

Room 3 =

• TV with IR
• Wall-control for whole-house amp with IR control

The HDMI matrix inputs are HTPC, AVR's output (VideoProcessor) and a VM