I make a point of power cycling an item no more than once a day. (Unless I’m testing a control system) I agree that power up is very stressful. With respect to booting the hard drive, the drive goes to sleep after a while. Waking is nearly as stressful as power up. Certainly, one could make a point that there is quite a lot of disk activity during boot up. It’s a voice coil driven head and there is very little wear for seeks.