I too purchased an Insignia Tv from bestbuy. I got the IS-TVHD30. If you have comcast set up is simple. Get your comcast remote. Press TV. Then hold setup until the tv light blinks twice. Then enter code 9-9-1. The TV light should flash twice. Then press "POWER" then "TV" alternate this until your TV turns off. (EX. "POWER" "TV" "POWER" "TV" until your tv turns off).... this took me about 40 times. ONCE YOUR HAVE THE CODE AND YOUR TV HAS TURNED OFF, press the setup button to store the code. (you may accidentally skip over the code it find because your trying to find the code, just repeat until your find it again but go slower).

I hope this helps, it took me about 20 mins to finally figure out how to program the damn thing!