Ok, I just got it a few days ago and I'm pretty happy, with the exception of a few issues, ones I'm sure can be solved somehow.

#1
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When I hit Watch TV, it turns on the TV instantly, and then takes like 10+ seconds of holding the remote aiming it at the stereo before it turns it on. I tried changing the power-on delay of the stereo to 100ms, as it was originally set at 15000ms, and that didn't fix it. My TV has a high power-on delay also, so I thought maybe the remote was turning on the TV, then waiting for that delay to expire before turning on the stereo. So I changed the power-on order and put the stereo ahead of the TV. That didn't change anything either, it still turns on the TV first, waits a while, then turns on the stereo. It's really annoying having to keep the remote aimed at the entertainment center so long.

#2
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My stereo is a Phillips mini-DVD combo system. By default the Harmony application only has settings for 4 out of about 8 available inputs. I got the remote to learn all the inputs I need with the exception of one. Aux and the digital input are on the same button on the stereo remote. You hit it once and it goes to Aux, wait a few seconds, then hit it again to get it on the digital input. My media PC is on the digital input, so when I want to get everything on for the media PC I need it to switch to that. I've got the Aux button learned, but since they're the same button, how can I get it to hit the button twice with a delay in between?

#1 Did you try reducing the interdevice delay

#2 I think for this you would need to contact Logitech Support to make this work