This remote looks as it could be a nice improvement to the older Harmonys (button layout, shape, etc.), but what I really don´t like about this new remote is:
why the hell must they use this shinny, glossy material for it? Every fingerprint will be seen on it. This item will be used a lot and also on the photos it looks like they have dipped it into cheese....and I don´t buy a remote just for cleaning :D

And just for information: also I would prefer a remote including coloured (hard) buttons much more than this "One" ;) - and rubber/gemstone buttons would be desirable

in general this means for me, that I either have to wait for the next Harmony, perhaps non-glossy and with coloured buttons - or I have to look for other brands....