Try this.
21. I need to update my remote's firmware in safe mode, how do I do it?

start the software on your computer
remove battery from remote
press and hold the off button
connect the remote to the USB cable
when remote is connected it should show "Safe Mode" in the LCD (power is provided by USB at this time)
release the off button
initiate a firmware update in the software
after successful firmware update, update the remote with your settings
disconnect the remote from the USB cable
reinsert the battery in the remote
wait for the remote to come up