I am pretty picky when it comes to remotes. I think the TPMC-3X is a great remote. I hated the fact that the hard button set was so limited but once i got my hands on it i didn't mind. I think the side trigger is a great idea.
Having said that.. the PLX2 is a very nice remote. I never got my hands on one but i did get to play with a Denon look alike. Great set of hard buttons and feels very nice in your hand.