If you're willing to spend $250 on an H/K, I think your money would be better spent on the MX-500.
It has regular buttons for all the regular functions (numbers, transport, etc), it has a thumbpad/joystick thing for the navigation (which I don't personally like), and it has an LCD screen with 10 extra buttons around it, which you can program with up to 20 additional functions per device, of which there are 10.
It has built in codes, which kinda suck, but it has TONS of learning memory, so that's not really a problem.
Having said all that, personally I have more than enough buttons on my $30 15-1994 remote to control all 13 devices in my system.
Rob
http://www.hifi-remote.com