1. Software works with Vista. You need a serial port and the cable. If you've lost the cable see
[Link: surfremotecontrol.com].
If you don't have a serial port get a USB-Serial Adapter, some people say they've had luck with the RadioShack one, URC recommends Belkin and Keyspan.
2. The only things you can do without a computer are learn codes to buttons and reprogram Favorites. Press and hold MAIN + ENT until the setup menu appears.