Its a preprogrammed remote, you're stuck with whatever's mapped via the preset code.
Unlike the similar looking Inteset 422-3, which takes advanced codes(efc) for individual functions. Say you want Disney+ key for your roku, all you do is:
1. roku device
2. press and hold set for two blinks, release
3. enter 9 9 4
4. tap set for one blink
5. enter 0 0 0 7 0
6. pick a key
Can't do that with Anderic remote.