I am using Mx500 with SONY t-60 intergrated Tivo, a Sony HD sat receiver, and an RCA 480 Sat(all on the same Mitz 65 HD TV), a JVC SVHS VCR, and a Phillips progressive scan DVD. MX 500 works very well with all devices including pic in pic etc. Takes some thought and planning but I feel it is far easier to use on regular basis and also to program then the screen based products such as Pronto. What I really need now is someway for it to talk to my Bose Lifestyle 50 which is RF(screen based also which is why I dislike these type of devices so much) only and I am forced to use its silly remote once in a while. I am going to post a separate inquiry on this problem to be able to do a an IR to RF transmission conversion.