If you have a TSU3X00, TSU7X00, or equivalent, this post really should be in the Next Generation Forum.
In the NG forum, I believe I have a detailed thread about the driver. I recently installed PPENG and I believe it had a folder under the location where it installed for drivers. Note that only the TSU7X00 remotes require a driver the TSU3X00 remotes used the HID drivers from Windows.
Here are a couple of links for the 7000 series driver.[Link: remotecentral.com][Link: remotecentral.com]
If you'd like me to move the thread to that forum, please indicate such and I will move it.
With regard to your question about working with Windows 10, Philips has not touched this software since circa 2004. Some folks have gotten it to work with Windows 10. I personally still use Windows 7 32 bit for my Pronto work but suspect in the very, very near future, I will move to Windows 10. As I only have Pro Remotes remaining, I am very hopeful that I can continue my efforts on Windows 10.