I converted my file so all the macros and other button references use ir database links rather than aliasing to the device buttons. I downloaded both to the remote, and the 2 approaches used essentially the same amount of memory. This is a simple system with a receiver, BluRay, and a TV. It is however probably a pretty common configuration for 780 users. At least in this simple experiment, using ir database links rather than aliasing did not use more memory than aliasing. So, I will stick to database links, which then allows me the option to move the device buttons as needed.