Total Control Accelerator is a wizard, but system design and engineering is much more important because it is intended as a whole house control and automation solution. If you have some control theory experience and read all of the documentation included in the software package you can install and program it yourself. That being said, you have to design and understand control and automation theory first before you start buying parts and programming. It's not as simple as buying a MRX-10 and TRC1280 and adding some IR codes to it.

That being said, the MX5000 is an OK remote, but its wifi capability is best suited for use with the PSX2 iPod dock for 2-way metadata (there is a URC driver written for it in CCP), you can install the little news and weather widgets on it through CCP, and if there is a driver for it you can see volume control and radio station preset info on the screen if your AVR has IP control Nd there is a driver for it. Network latency make for sluggish feel of volume and channel commands with that remote over wifi, not to mention the network has a tendency to go to sleep after a certain period of time to preserve the battery charge.

All current URC remotes work with the URC lighting devices. They are easy to program, easy to install and work well for blind, 1-way control.

Personally I'd avoid the MX5000 and get a MX980 or MX1200. Or, as I'm waiting for it, a MXiOS license and MRX-1 base station and use your iPad or iPhone as a remote. Very customizable and has more powerful macro features than even Total Control does right now. That should be shipping in a couple of weeks.