I've used/programmed both the mx5000 and the S70.  the mx5000 is one of my favorite remotes.  the S70...not so much.   The extra hard buttons on the mx5000 make it much easier to use.  the screen is larger on the s70, but it has the same resolution as the mx5000, so the graphics aren't as crisp on the s70.   The color of the the mx5000 screen is much more accurate as well.

have you actually used the Sonos app on the S70?  i've heard it is clunky and no where near the same as a Sonos controller.  

what don't you like about the 5000?

by the way, Nevo is not done with that remote line.  they just don't sell the Q50 to the US market anymore.