You may be disappointed with Harmony One after having a Yamaha RAV remote. They are not as customisable.

You may have trouble getting software for a MX980 unless you find a authorised dealer that are willing to supply it.

Other options,
Nevo Q50 or S70
Philips Pronto TSU9300, TSU9400, TSU9600, TSU9800.

Philips Pronto has been discontinued/closed down but they may find buyer to continue. They are still honouring warranties though.

PEP2.4 Software for Pronto's is here on RC if you want to take a look.


Cheers
Jason