I spoke with Phillips support today and was basically told try right clicking prior to running setup and checking the compatibility box for "XP" (even though I run vista) If that doesn't work "too bad but the remote has been discontinued". It's a great remote but if they intend to stop making drivers for remotes when MS updates their os...then I have no choice than to look for another brand I guess.

Too expensive to have to replace when it's working perfectly well...except when I need to run it with VISTA.

It really will make me think long and hard before investing in another phillips remote product. Very disappointing.