64MB of memory
More Hard Buttons (New Power Hard Button & Page Up,Page Down are now programmable)
Screen with pixel density 4x the size of the NG screen
Landscape screen 640x480, not a portrait screen of 240x320
The ability to play WAV files
More solid IR learning capabilities
The ability to interface with Escient Music Servers
The ability to interface with Lutron Lighting Systems
Better backlight control (user can control which things activate the backlight)
USB 2.0 compliance

Both the software and manuals are available for download. You should try it out before you buy.

You might also want to read the Cedia Notes posted to the left under What's New.

[Link: remotecentral.com]