Two Way Comms is possible, but as buzz has pointed out: If you want to do it you're going to need to do some javascript / prontoscript programming. You would also need either an RFX9600 or use a PC to act as the go-between. The RS232 codes that can be set in MyDatabase are one way and do not wait for / or process any response from the connected equipment.
Regarding newest components: I have two components that both have RS232 firmware dating back to 1998 and they are both capable of two way comms! Buzz, I'm not sure what you are referring to wrt 'newest components', if it's the Pronto side I agree with you; if it's equipment being controlled by the Pronto.........
You can hide almost anything until you have to put the drywall up!