Hi Neil,
It could be a combination of RF and the IR sensitivity of the components (like the Integra and cable box) that are the worst offenders. Try moving the emitters away somewhat from the IR receiving eyes. I've pretty much stopped using MRF-250s for these reasons. Also, check out the RF solution in the thread below here:
[Link: remotecentral.com]Mike
www.SurfRemoteControl.com