I see that the MSC-400 has a IR input which it blasts out on all ports. Is there any way to do any routing with the IR at all, like some of the Xantech IR routers?

The RT8 for example has one IR in, and you can control which port to send the output to. One negative with this is that the programming is involved since a route has to be established per IR command and there is no concept of device level routes.

Perhaps another way to ask the question - how do you make the MSC-400 work with IR only remotes? Do they have pure IR Triggers?