I was able to get into contact with a Nevo rep and here's the latest information on controling an Escient system with a NevoSL:

1. Yes, it will definitely work, but you must make sure to upgrade the firmware on both the Escient system and the NevoSL unit.
2. From the remote, you will be able to browse the audio content only. Sorry, no DVD control support yet.
3. Album art (appearing on the NevoSL) is not supported at the moment though.
4. When controling the Escient through the NevoSL (meaning, when you create a "media zone" in NevoStudio software), the Escient will only be the server, and not the server and player. What they meant by this, is that at the moment, you can browse the Escient content and send it to another UPnP player (D-Link Media Lounge, NevoPlayer software running on a computer, etc.), but you cannot send the Escient content to play through any of it's outputs.

Granted, this system doesn't have all the bells and whistles yet, but for NevoSL to be the first remote that can do this, I think it's pretty cool.