No reason not to try one. But be aware that using 2 in the same room will cause issues since each remote will be keeping track of the status of each device. e.g. If you select an activity on remote 1, then go to remote 2 you'll have to select the activity again on remote 2 which will try to turn all the devices on and set the right inputs. You could select the activity while blocking the IR emitter but you'll have to do the same thing when turning things off or selecting another activity. If your equipment uses discretes for everything (power and inputs) then you can get away with resending the activity commands but not with toggles.
The software now has a local GUI that replaces the browser interface (but you can still use the website interface). It is a little better but it still needs the internet connection and still stores the configuration in the harmony database.