Well, that depends. If you're referring to simply putting plugs on the ends of CAT-5 cable, then you will suffer poor signal quality.
However, as is done on lond-line data links, with the proper tranceivers, signals can indeed travel over twisted-pair wiring with little signal degradation.
Those of us with DSL computer service are living proof. These signals can travel over miles of wire pairs.
Larry
www.fineelectricco.com