Mike,
Below is the basic setup of the navigation buttons from PDAWin.
In CCF mode, PDA buttons are assign as follows:

keypad up: + volume.
keypad down: - volume.
keypad left: - prog. ch
keypad right: + prog. ch
keypad middle: mute
another 4 keys are placed as they are in ProntoProEdit.
I have mine setup so that the up, down, left, right and enter buttons use the navigation pad and I use 2 of the 4 hard buttons for volume + and - and the other 2 hard buttons to dim and brighten my X10 lights.
As far as the Axiom waking up in TV Remote Controler, I have the home button (the far right button) set so that when the Axiom is asleep and you press the home button it automatically wakes up in the TV Remote Controller program.
Hope that helps, Arnie...