I'm trying to decide which remote to buy next, so I have been reading about the MX-1000 with interest. My two cents on the power button:

It is my opinion that many people buying a higher-end remote would prefer All On and and All Off buttons. This allows the use of discrete codes when available and eliminates the problems that Kimo alluded to above regarding the current state of your components.

So, what if that big power button were split in two; left side is On, right side is Off ( and slightly recessed so it is harder to hit.) Both buttons would be macro buttons. In this scenario I would bury the individual power buttons on the LCD, since they would be used infrequently. I would use my Cinema 7 to teach discrete On and Off commands to the LCD as well, allowing them to be incorporated in the All On and All Off macros.

Users who don't like this scenario could still use the Power On hard button to power each individual component if they choose.