Yes, as long as you have discrete on/off codes for your equipment. The 850 doesn't support variables so the remote can't "GUESS" weather a component is on or off like the harmony.
We only sell equipment with discretes, so this is how we program our 850s, only the equipment that is needed is powered on.
There are 10 types of people in this world, There are those who understand binary, and those who don't!