Mainly you have to make sure you don't amplify too strong before running through other amps. So, if your signal is +10db at the start, you don't want to add a +20db amp on top of that and THEN run it through an 8200 since that would overwhelm it. But it's unlikely to be +10.

I would try one good amp right at the beginning. If that doesn't work or goes too strong, try splitting and then running *two* amps, one on each leg, before getting to the distribution amps.