Indigo will react to X10 commands and take actions from them. Send a double press A-1, A-1 with your remote pointed at the IR-543 and instruct Indigo to output a scene sequence. When I do a master off once it locally switches off all lights in the room, but if I press it twice it sequences and shuts off all lights in my house. Another trick is to allow Indigo to eliminate a step to turn on a local light. Pressing one button say B-1 will trigger Indigo to issue the generic "on" command so you don't have to press another button on the remote. Only drawback is you have to use all-off to turn off the light instead of individually for that room.