I had the same concern while my house was being built.
I surfed around on the net and happened upon some helpful advice. I've placed a link at the bottom of this message to an excel spreadsheet file that will help you determine the optimal placement of your speakers in relation to your room size.
I used it for my set-up and it worked great! Hope this is helpful to you!
Sincerely,
Scott
Here's the link:
[Link: guidetohometheater.com]