I have the 5/1 set up in the livingroom with 2 frontal 1 center speaker and 2 speakers in the rear of the room all wired but no wires are seen anyplace.

The subwoofer is located in the center compartment down below of the entertainment center.
The 2 rear speakers are mounted on microphone's stands with 12" round bases for stability and height adjustability of the speakers.

The speaker wire is the usual flat brown wire which is ran underneath 2 transitions by the doors and the rest is tucked all the way in between the wall and the carpet and you'll never know the wire is there.

Now I don't know the lay out of your rooms and doors, but if you plan it right you might have a chance of a similar set up.
J. Bond