I have the same remote, when I went to best but they said no code for isignia. Guess what?? They were wrong. just one thing , do code serch and please be patient. because it does work!!!! That is how I got mine to work with isignia tv. Trust me on it. I have had remote for 2 years now and it works, actualy I have everything working with it, cable, dvd, vhs, even my stereo... They say no I tried and yes it does.The only thing is do code serach and be very patient. It will work for yopu also. I called best but and told them it does work they had nothing to say.... PLEASE try it. I wish I had the code to send but with code search I never bothered to check what code was used. Go ahead .. and let me know.