"System" I did recently. Sony OLED Denon AVR (w/HEOS) Appletv 4k Xbox One
The Appletv remote happily and reliably turned the display and AVR on/off and adjusted AVR volume HEOS app integrated house audio in the surround zone with the other 3 HEOS players in the home. The only thing they needed to involve another remote for was to go to the Xbox (seldom used) or to make audio adjustments (that most people never do).
A house in this market segment used to be as follows: 1. Display* 2. AVR* 3. Speakers* 4. DVD/Bluray player 5. Power/surge protection* 6. House audio source gear (CD, XM tuner etc) 7. House audio amplifier or multi source, multi zone system (Russound or RTI)* 8. Keypads or house audio control panels of some sort* 9. Remote and processor* 10. Rack, rack shelves, thermal management* 11. Control system programming*
* products and services that had good margin at the time.
Now it is 4-5 devices, most on no/slim margin and most with little to no programming labor.
I am a trained professional..... Do not attempt this stunt at home.