Speaking of TSA -- If you air freight something that goes on regular airlines, do they have the right to inspect it as well?

In my corporate world, we sometimes do NFO (Next Flight Out) for hard down tools for which we don't have replacement items in stock.
Some of those parts are sensitive to light, dust, etc.
All the parts that are on NFO system fly regular commercial flights (we can track progress from shipper to our reception).
Is there a system where parts skip inspection or get special treatments to avoid opening them?
Some parts may be prototypes or industry secrets.
I do know that some really sensitive parts will have chaperone. Someone will buy 2 seats next to each other and chaperone takes one and the box takes the other seat.