Yes, there is a driver available which takes advantage of Samsung's Ex-Link port in back which is basically a 3.5 to serial port. There is a proprietary cable you can order from Samsung although many guys make them on their own. Control is not inclusive of all commands, however, all discrete power and inputs make for great control. If you want some of the Smart Hub commands you may have to go IR. Rarely do my customers use those features anyway.

If you are new to RTI consider SONY KDL B & C series televisions. RTI just came out with a driver that works great.