check the IP address in the TCP/IP client symbol, try and ping the V+ from the processor.

Is that port correct?

you have a 1 on the TCP/IP_Connect signal on the client symbol?

Sounds like everything SHOULD be working....wait the commands are just ASCII?

Do you have the commands in the SIO ending with a \x0D? or do you have the Delimiter in the SIO set to \x0D?

I think your problem is you are NOT sending the carriage return in SIMPL