Ok well I have the below equipment and just did a full wall unit with all new everything and Yes the 64f8500 remote is nice and does alot, and the Onkyo NR929 remote is nicer and does even more, neither/none of them does it all.

Wife is pissed that I have about 5K in just equipment and we have to use 3 remotes minimum to work it all.

I have tried other removes in the past and NONE seemed to be able to do it all, due to having something brand new and new codes or something.

I bought the MX-450 and now need to get it to do everything.

Is there a way to do programming in a user available software and then just upload it in to the remote? I see theres a USB port under the battery door.

I have:
TV - Samsung 64f8500
DVD/BR - Samsung BD-F7500
AVR - Onkyo TX-NR929
SAT - Dish Hopper
X-Box

Thank you
Robert