Ok, the current 880 has been great for the past 6 years, but it's beginning to die. It sometimes needs the battery to be reinserted to work, the firmware went hay-wire during a programing, among other things.
It's dieing for a number of reasons, one being that someone would fall asleep with the remote in had, and sweat.

Preferably, I want to be able to program it myself as if anything changes in the current setup, I don't want to pay anyone to re-program it.

Samsung TV LN52A750R1F
Onkyo TX-NR509
LG BP-530
Comcast cable box

I need it to do everything the 880 does.
It needs physical buttons.
It needs to be able to switch activities without an issue, leaving things on if they already one as well as offering a "help button" just in case.
It needs a master "off" button that will turn everything off except the cable box.
Needs to be able to withstand drops.

The reason being my mother will be using it, and it needs to be easy to use. If things get out of sync, it needs to be easy to get them back in sync.

I have heard some bad things about the Harmony Touch, so I want to avoid that one.

Budget should be as low as possible, maxed out at around $250