There is one of the settings made using the dip switches that gives two shade controls, one with up, down & stop and one with up & down. Set the dip switches to this setting. You MUST use a flywheel diode or contact suppression unit or interface unit otherwise your relay contacts in the QSE-IO will be very short lived!
If you want the output to run from a key press on a QS keypad and you have a base unit without shading (and no shading controls) then you could set the button on the keypad as an unused scene (such as scene 10) even if the base unit only has 4 scene controls. You can then set the QSE-IO to trigger a relay output for a scene press and within the software set the scene to not make any changes to the other zones. It is a work around but not ideal. If you do this it may be worth investing in a CD4 module to make sure the signal to the three wire control does not get mixed up! My suggestion is go for shade control (including keypads) and use the 3+2 option.